Assertion : Type I restriction endonucleases are not used in recombinant DNA technology.
Reason : Type I restriction endonucleases recognise specific sites within the DNA but do not cut these sites.
Answer (a) Both assertion and reason are true and reason is the correct explanation of assertion.
Reason (a) : Restriction endonuclease are enzymes that cleaves DNA at specific sites along the molecule. Type I restriction enzyme recognises specific DNA sequences but make their cut at seemingly random sites that can be as far as 1000 base pair away from the recognition site.